Tbio GPKOW G-patch domain and KOW motifs-containing protein

Protein Summary

Description

RNA-binding protein involved in pre-mRNA splicing. This gene encodes a putative RNA-binding protein containing G-patch and KOW (Kyprides, Ouzounis, Woese) domains. The encoded protein interacts directly with protein kinase A and protein kinase X and is also found associated with the spliceosome. [provided by RefSeq, Aug 2013]

Uniprot Accession IDs

• Q92917
• Q59EK5
• Q9BQA8

Gene Name

• GPKOW

Ensembl ID

• ENST00000156109
• ENSP00000156109
• ENSG00000068394

Symbol

• GPATC5
• GPATCH5
• T54
• T54
• Spp2
• GPATC5
• GPATCH5

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.85
histone modification site profile	0.84
interacting protein	0.67
tissue sample	0.64
microRNA	0.6

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / G-patch Domain And Kow Motifs-containing Protein

DTO Classes

Protein / Nucleic Acid Binding / G-patch Domain And Kow Motifs-containing Protein

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.46   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 165   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.46   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 165   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0