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Tbio
RPL3L
60S ribosomal protein L3-like

Protein Summary
Description
This gene encodes a protein that shares sequence similarity with ribosomal protein L3. The protein belongs to the L3P family of ribosomal proteins. Unlike the ubiquitous expression of ribosomal protein genes, this gene has a tissue-specific pattern of expression, with the highest levels of expression in skeletal muscle and heart. It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000268661
  • ENSP00000268661
  • ENSG00000140986
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.9
biological process
0.71
cell line
0.6
cell type or tissue
0.59
cellular component
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.13   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 60   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.13   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 60   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (384)
RPS16
Tbio
Novelty:  0.00261983
Score:  0.999
Data Source:  STRINGDB
RPS26
Tbio
Novelty:  0.0183394
Score:  0.999
Data Source:  STRINGDB
RPL8
Tbio
Novelty:  0.01064076
Score:  0.999
Data Source:  STRINGDB
RPL9
Tbio
Novelty:  0.00845583
Score:  0.999
Data Source:  STRINGDB
RPL30
Tbio
Novelty:  0.0134194
Score:  0.999
Data Source:  STRINGDB
RPL24
Tbio
Novelty:  0.02160548
Score:  0.999
Data Source:  STRINGDB
RPL18
Tbio
Novelty:  0.01765545
Score:  0.999
Data Source:  STRINGDB
RPL6
Tbio
Novelty:  0.01742007
Score:  0.999
Data Source:  STRINGDB
RPL11
Tbio
Novelty:  0.00448962
Score:  0.999
Data Source:  STRINGDB
RPL4
Tbio
Novelty:  0.00475169
Score:  0.999
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (34)
Axon guidance (R-HSA-422475)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 32
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Reactome
Eukaryotic Translation Elongation
Name
Explore in Pharos
Explore in Source
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Eukaryotic Translation Elongation
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
1
3
3
92
glomerular filtration rate
2
2
2
78.7
2
3
0
1.1
77.8
hemoglobin measurement
2
1
2
75.6
red blood cell density measurement
1
1
1
71.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
3
92
glomerular filtration rate
2
78.7
0
1.1
77.8
hemoglobin measurement
2
75.6
red blood cell density measurement
1
71.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ribosomal protein L3 like
VGNC:5913
746600
Macaque
ribosomal protein L3 like
693424
Mouse
MGI:1913461
66211
Rat
RGD:1306315
287122
Horse
ribosomal protein L3 like
VGNC:22530
100068030
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ribosomal protein L3 like
Macaque
ribosomal protein L3 like
Mouse
Rat
Horse
ribosomal protein L3 like
Publication Statistics
PubMed Score 6.13
PubMed score by year
PubTator Score 2.55
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title