Protein Summary
Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity).
- ENST00000314744
- ENSP00000317580
- ENSG00000181965
- BHLHA6
- NEUROD3
- NGN
- NGN1
- AKA
- ngn1
- Math4C
- bHLHa6
- NEUROD3
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.79 | ||
PubMedID | 0.68 | ||
molecular function | 0.63 | ||
transcription factor binding site profile | 0.58 | ||
cell type or tissue | 0.53 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 213.16 (req: < 5)
Gene RIFs: 13 (req: <= 3)
Antibodies: 535 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 213.16 (req: >= 5)
Gene RIFs: 13 (req: > 3)
Antibodies: 535 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 33
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0