GOLGA1
Golgin subfamily A member 1
Protein Summary
Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein is associated with Sjogren's syndrome. [provided by RefSeq, Feb 2010]
- ENST00000373555
- ENSP00000362656
- ENSG00000136935
- golgin-97
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 0.97 | ||
histone modification site profile | 0.92 | ||
microRNA | 0.77 | ||
transcription factor binding site profile | 0.77 | ||
disease perturbation | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 33.07 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 162 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 33.07 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 162 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (90)
SYCE1
Novelty: 0.05038876
p_int: 0.999984915
p_ni: 1.4e-8
p_wrong: 0.000015071
Data Source: BioPlex
Nearest Tclin Targets
Pathways (4)
Reactome (4)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Reactome | Membrane Trafficking | ||||
Reactome | Retrograde transport at the Trans-Golgi-Network | ||||
Reactome | Vesicle-mediated transport | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Intra-Golgi and retrograde Golgi-to-ER traffic | ||||
Membrane Trafficking | ||||
Retrograde transport at the Trans-Golgi-Network | ||||
Vesicle-mediated transport | ||||
Viral Interactions (0)
Gene Ontology Terms (6)
Components (6)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Direct Assay (IDA) | HPA | |||
Inferred from Direct Assay (IDA) | CACAO | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-SubCell | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-SubCell | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Disease Associations ()
GWAS Traits (2)
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 0 | 7.1 | 71.6 | |||||
IGF-1 measurement | 1 | 1 | 1 | 35 | |||||
Items per page:
1 – 2 of 2
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
0 | 7.1 | 71.6 | |||||
IGF-1 measurement | 1 | 35 | |||||
Find similar targets by:
IDG Resources
Orthologs (14)
1 – 5 of 14
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | golgin A1 | VGNC:4754 | 464730 | |||||
Macaque | golgin A1 [Source:HGNC Symbol;Acc:HGNC:4424] | |||||||
Mouse | MGI:1924149 | 76899 | ||||||
Rat | RGD:1311305 | 311919 | ||||||
Dog | golgin A1 | VGNC:41338 | 480728 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | golgin A1 | |||||
Macaque | golgin A1 [Source:HGNC Symbol;Acc:HGNC:4424] | |||||
Mouse | ||||||
Rat | ||||||
Dog | golgin A1 | |||||
Publication Statistics
PubMed Score 33.07
PubMed score by year
PubTator Score 16.91
PubTator score by year
Related Publications
Text Mined References (19)
GeneRif Annotations (8)
Items per page:
0 of 0
PMID | Year | Title |
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