Tbio GOLGA1 Golgin subfamily A member 1

Protein Summary

Description

Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein is associated with Sjogren's syndrome. [provided by RefSeq, Feb 2010]

Uniprot Accession IDs

• Q92805
• Q5T164
• Q8IYZ9

Gene Name

• GOLGA1

Ensembl ID

• ENST00000373555
• ENSP00000362656
• ENSG00000136935

Symbol

• golgin-97

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.97
histone modification site profile	0.92
microRNA	0.77
transcription factor binding site profile	0.77
disease perturbation	0.68

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.42   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 162   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 38.42   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 162   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0