GOLGA1
Golgin subfamily A member 1
Protein Summary
Involved in vesicular trafficking at the Golgi apparatus level. Involved in endosome-to-Golgi trafficking. The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This encoded protein is associated with Sjogren's syndrome. [provided by RefSeq, Feb 2010]
- ENST00000373555
- ENSP00000362656
- ENSG00000136935
- golgin-97
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
virus perturbation | 0.97 | ||
histone modification site profile | 0.92 | ||
microRNA | 0.77 | ||
transcription factor binding site profile | 0.77 | ||
disease perturbation | 0.68 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 38.42 (req: < 5)
Gene RIFs: 10 (req: <= 3)
Antibodies: 162 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 38.42 (req: >= 5)
Gene RIFs: 10 (req: > 3)
Antibodies: 162 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Term: 0
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0