RND1
Rho-related GTP-binding protein Rho6
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.93 | ||
transcription factor binding site profile | 0.8 | ||
histone modification site profile | 0.76 | ||
virus perturbation | 0.72 | ||
disease | 0.71 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Axon guidance | ||||
Reactome | Developmental Biology | ||||
Reactome | SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | ||||
Reactome | Sema4D in semaphorin signaling | ||||
Reactome | Sema4D induced cell migration and growth-cone collapse | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Axon guidance | ||||
Developmental Biology | ||||
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion | ||||
Sema4D in semaphorin signaling | ||||
Sema4D induced cell migration and growth-cone collapse | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 2 | 2 | 73.4 | |||||
bone density | 1 | 1 | 2 | 49.5 | |||||
testosterone measurement | 1 | 1 | 1 | 28.1 | |||||
self reported educational attainment | 1 | 1 | 1 | 4.5 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
heel bone mineral density | 2 | 73.4 | |||||
bone density | 2 | 49.5 | |||||
testosterone measurement | 1 | 28.1 | |||||
self reported educational attainment | 1 | 4.5 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | Rho family GTPase 1 | VGNC:5572 | 466975 | |||||
Mouse | MGI:2444878 | 223881 | ||||||
Rat | RGD:1306338 | 362993 | ||||||
Dog | Rho family GTPase 1 | VGNC:45616 | 477623 | |||||
Horse | Rho family GTPase 1 | VGNC:22421 | 100058747 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | Rho family GTPase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | Rho family GTPase 1 | |||||
Horse | Rho family GTPase 1 | |||||
PMID | Year | Title |
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