MYO18A
Unconventional myosin-XVIIIa
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.99 | ||
interacting protein | 0.98 | ||
protein domain | 0.92 | ||
transcription factor binding site profile | 0.88 | ||
drug perturbation | 0.87 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Disease | ||||
Reactome | Diseases of signal transduction | ||||
Reactome | FGFR1 mutant receptor activation | ||||
Reactome | Signaling by FGFR in disease | ||||
Reactome | Signaling by FGFR1 in disease | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Disease | ||||
Diseases of signal transduction | ||||
FGFR1 mutant receptor activation | ||||
Signaling by FGFR in disease | ||||
Signaling by FGFR1 in disease | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
smoking status measurement | 2 | 2 | 3 | 77.8 | |||||
3 | 2 | 0 | 1 | 69.6 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 63.7 | |||||
BMI-adjusted hip circumference | 1 | 3 | 3 | 60.9 | |||||
mathematical ability | 2 | 2 | 3 | 55.8 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
smoking status measurement | 3 | 77.8 | |||||
0 | 1 | 69.6 | |||||
mean reticulocyte volume | 1 | 63.7 | |||||
BMI-adjusted hip circumference | 3 | 60.9 | |||||
mathematical ability | 3 | 55.8 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | myosin XVIIIA | VGNC:12492 | 100615253 | |||||
Macaque | myosin XVIIIA | 711171 | ||||||
Mouse | MGI:2667185 | 360013 | ||||||
Rat | RGD:1562698 | 360570 | ||||||
Dog | myosin XVIIIA | VGNC:43557 | 480630 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | myosin XVIIIA | |||||
Macaque | myosin XVIIIA | |||||
Mouse | ||||||
Rat | ||||||
Dog | myosin XVIIIA | |||||
PMID | Year | Title |
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