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Tdark
MAFIP
MaFF-interacting protein

Protein Summary
Description
Acts as coactivator of MAFF transcriptional activity. Inhibits cell growth and colony-forming efficiency. This gene was originally thought to be a protein coding gene. However, the encoded protein sequence is highly similar to the C-terminal sequence of the tektin-4 protein, and the transcript sequences of this gene are highly similar to the TEKT4 pseudogenes, which are found on chromosomes 4, 21 and Y, respectively. Therefore, this gene is thought to be another pseudogene of the TEKT4 gene (GeneID:150483). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
Uniprot Accession IDs
Gene Name
Symbol
  • MIP
  • MIP
  • pp5644
  • TEKT4P4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue
0.47
transcription factor
0.42
biological term
0.34
interacting protein
0.31
PubMedID
0.19


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.76   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.76   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8WZ33-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (6)
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (9)
1 – 9 of 9
OR6C4
Tdark
Family:  oGPCR
Novelty:  5.07120743
Score:  0.789
Data Source:  STRINGDB
ZNF440
Tdark
Family:  TF
Novelty:  1.47044342
Score:  0.681
Data Source:  STRINGDB
PLEKHA3
Tbio
Novelty:  0.06598909
Score:  0.533
Data Source:  STRINGDB
SRPRA
Tchem
Novelty:  0.01248718
Score:  0.53
Data Source:  STRINGDB
MIS18A
Tbio
Novelty:  0.08143008
Score:  0.529
Data Source:  STRINGDB
GCSH
Tbio
Novelty:  0.02101972
Score:  0.527
Data Source:  STRINGDB
IKBKG
Tbio
Family:  Kinase
Novelty:  0.0006149
Score:  0.489
Data Source:  STRINGDB
TEKT2
Tbio
Novelty:  0.04607893
Score:  0.438
Data Source:  STRINGDB
MAFF
Tbio
Family:  TF
Novelty:  0.01974936
Score:  0.437
Data Source:  STRINGDB
Publication Statistics
PubMed Score  2.76

PubMed score by year
PubTator Score  0.83

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer