Protein Summary
Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.
- ENST00000326225
- ENSP00000355465
- ENSG00000153207
- ENST00000366508
- ENSP00000355464
- ENST00000648844
- ENSP00000497061
- ELYS
- TMBS62
- ELYS
- MST108
- TMBS62
- MSTP108
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cellular component | 0.91 | ||
histone modification site profile | 0.88 | ||
ligand (protein) perturbation | 0.83 | ||
disease perturbation | 0.79 | ||
transcription factor binding site profile | 0.79 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 41.57 (req: < 5)
Gene RIFs: 4 (req: <= 3)
Antibodies: 100 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 41.57 (req: >= 5)
Gene RIFs: 4 (req: > 3)
Antibodies: 100 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 8
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (150)
IL13RA2
Novelty: 0.03465642
p_int: 0.829186742
p_ni: 0.170813257
p_wrong: 1e-9
Score: 0.183
Data Source: BioPlex,STRINGDB
VAPA
Novelty: 0.00169209
p_int: 0.760977217
p_ni: 0.239022783
Score: 0.163
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (22)
Reactome (16)
WikiPathways (6)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Reactome | Amplification of signal from the kinetochores | ||||
Reactome | Cell Cycle | ||||
Reactome | Cell Cycle Checkpoints | ||||
Reactome | Cell Cycle, Mitotic | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal | ||||
Amplification of signal from the kinetochores | ||||
Cell Cycle | ||||
Cell Cycle Checkpoints | ||||
Cell Cycle, Mitotic | ||||
Viral Interactions (0)
Gene Ontology Terms (16)
Functions (2)
Components (8)
Processes (6)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Sequence Model (ISM) | NTNU_SB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (1)
Items per page:
1 – 1 of 1
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean platelet volume | 1 | 1 | 1 | 70.5 | |||||
Items per page:
1 – 1 of 1
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean platelet volume | 1 | 70.5 | |||||
Find similar targets by:
IDG Resources
Orthologs (10)
1 – 5 of 10
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | AT-hook containing transcription factor 1 | 702705 | ||||||
Mouse | MGI:1915033 | 226747 | ||||||
Rat | RGD:1561291 | 360886 | ||||||
Dog | AT-hook containing transcription factor 1 | VGNC:37723 | 480106 | |||||
Horse | AT-hook containing transcription factor 1 | VGNC:15177 | 100054592 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | AT-hook containing transcription factor 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | AT-hook containing transcription factor 1 | |||||
Horse | AT-hook containing transcription factor 1 | |||||
Publication Statistics
PubMed Score 41.57
PubMed score by year
PubTator Score 12.84
PubTator score by year
Related Publications
Text Mined References (13)
GeneRif Annotations (4)
Items per page:
0 of 0
PMID | Year | Title |
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