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Tbio
AHCTF1
Protein ELYS

Protein Summary
Description
Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000326225
  • ENSP00000355465
  • ENSG00000153207
  • ENST00000366508
  • ENSP00000355464
  • ENST00000648844
  • ENSP00000497061

Symbol
  • ELYS
  • TMBS62
  • ELYS
  • MST108
  • TMBS62
  • MSTP108
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cellular component
0.91
histone modification site profile
0.88
ligand (protein) perturbation
0.83
disease perturbation
0.79
transcription factor binding site profile
0.79


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.32   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 100   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.32   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 100   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0