Tbio THAP4 THAP domain-containing protein 4

Protein Summary

Uniprot Accession IDs

• Q8WY91
• Q53NU7
• Q6GRN0
• Q6IPJ3
• Q9NW26
• Q9Y325

Gene Name

• THAP4

Ensembl ID

• ENST00000402136
• ENSP00000385931
• ENSG00000176946
• ENST00000407315
• ENSP00000385006

Symbol

• PP238
• CGI-36

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.91
kinase perturbation	0.81
cellular component	0.75
disease perturbation	0.74
histone modification site profile	0.74

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.49   (req: < 5)

Gene RIFs: 0   (req: <= 3)

Antibodies: 62   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.49   (req: >= 5)

Gene RIFs: 0   (req: > 3)

Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0