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Tbio
SLC7A3
Cationic amino acid transporter 3

Protein Summary
Description
Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner. This gene encodes a member of the solute carrier family 7. The encoded protein is a sodium-independent cationic amino acid transporter. Alternate splicing results in multiple transcripts that encoded the same protein.[provided by RefSeq, May 2010]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000298085
  • ENSP00000298085
  • ENSG00000165349
  • ENST00000374299
  • ENSP00000363417

Symbol
  • ATRC3
  • CAT3
  • CAT3
  • ATRC3
  • CAT-3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.73
PubMedID
0.65
virus perturbation
0.64
protein domain
0.58
molecular function
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 204.03   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 65   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 204.03   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0