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Tbio
BAALC
Brain and acute leukemia cytoplasmic protein

Protein Summary
Description
May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A. This gene was identified by gene expression studies in patients with acute myeloid leukemia (AML). The gene is conserved among mammals and is not found in lower organisms. Tissues that express this gene develop from the neuroectoderm. Multiple alternatively spliced transcript variants that encode different proteins have been described for this gene; however, some of the transcript variants are found only in AML cell lines. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297574
  • ENSP00000297574
  • ENSG00000164929
  • ENST00000306391
  • ENSP00000302559
  • ENST00000309982
  • ENSP00000312457
  • ENST00000330955
  • ENSP00000331579
  • ENST00000438105
  • ENSP00000395024
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.85
PubMedID
0.75
microRNA
0.62
kinase perturbation
0.6
tissue sample
0.54


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 50.97   (req: < 5)
Gene RIFs: 34   (req: <= 3)
Antibodies: 139   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 50.97   (req: >= 5)
Gene RIFs: 34   (req: > 3)
Antibodies: 139   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (8)
Items per page:
10
1 – 8 of 8
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
MGI
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (28)
1 – 10 of 28
MN1
Tbio
Novelty: 0.00146056
Score: 0.771
Data Source: STRINGDB
NPM1
Tbio
Novelty: 0.00069185
Score: 0.7
Data Source: STRINGDB
FLT3
Tclin
Family: Kinase
Novelty: 0.00045788
Score: 0.683
Data Source: STRINGDB
CEBPA
Tbio
Family: TF
Novelty: 0.00103676
Score: 0.669
Data Source: STRINGDB
WT1
Tbio
Family: TF
Novelty: 0.00042049
Score: 0.668
Data Source: STRINGDB
TOPAZ1
Tdark
Novelty: 0.291067
Score: 0.642
Data Source: STRINGDB
MYLK4
Tchem
Family: Kinase
Novelty: 0.55837563
Score: 0.625
Data Source: STRINGDB
GGA1
Tbio
Novelty: 0.01230282
Score: 0.599
Data Source: STRINGDB
CD34
Tbio
Novelty: 0.00007032
Score: 0.558
Data Source: STRINGDB
MAPKBP1
Tbio
Family: Enzyme
Novelty: 0.30679328
Score: 0.543
Data Source: STRINGDB
Publication Statistics
PubMed Score  50.97

PubMed score by year
PubTator Score  47.92

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer