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Tdark
LCN9
Epididymal-specific lipocalin-9

Protein Summary
Description
Members of the lipocalin family, such as LCN9, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000277526
  • ENSP00000277526
  • ENSG00000148386

Symbol
  • HEL129
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
tissue
0.58
cell line
0.53
drug
0.46
cell type or tissue
0.42


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.63   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.63   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
LCN8
Tbio
Novelty:  0.02098116
Score:  0.797
Data Source:  STRINGDB
CST11
Tbio
Novelty:  0.0327324
Score:  0.732
Data Source:  STRINGDB
OBP2A
Tbio
Novelty:  0.02757821
Score:  0.63
Data Source:  STRINGDB
LCN12
Tdark
Novelty:  0.31492521
Score:  0.615
Data Source:  STRINGDB
LCN10
Tdark
Novelty:  1.32107702
Score:  0.607
Data Source:  STRINGDB
LCN6
Tbio
Novelty:  0.11406686
Score:  0.599
Data Source:  STRINGDB
DEFB125
Tdark
Novelty:  0.69005738
Score:  0.589
Data Source:  STRINGDB
OBP2B
Tdark
Novelty:  0.43500456
Score:  0.583
Data Source:  STRINGDB
LCNL1
Tdark
Novelty:  7.94657763
Score:  0.57
Data Source:  STRINGDB
C16orf89
Tbio
Novelty:  1.14910379
Score:  0.554
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (4)
SLC-mediated transmembrane transport (R-HSA-425407)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 4 of 4
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
SLC-mediated transmembrane transport
Reactome
Transport of fatty acids
Reactome
Transport of small molecules
Reactome
Transport of vitamins, nucleosides, and related molecules
Name
Explore in Pharos
Explore in Source
SLC-mediated transmembrane transport
Transport of fatty acids
Transport of small molecules
Transport of vitamins, nucleosides, and related molecules
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
1
1
30.2
1
1
0
1.6
28.1
serum non-albumin protein measurement
1
1
1
6.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mathematical ability
1
30.2
0
1.6
28.1
serum non-albumin protein measurement
1
6.2
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
lipocalin 9
VGNC:13911
100615071
Macaque
lipocalin 9
711643
Mouse
MGI:1924954
77704
Rat
RGD:1306341
296578
Dog
lipocalin 9
VGNC:49710
607752
Species
Name
OMA
EggNOG
Inparanoid
Chimp
lipocalin 9
Macaque
lipocalin 9
Mouse
Rat
Dog
lipocalin 9
Publication Statistics
PubMed Score 4.63
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title