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Tbio
OIT3
Oncoprotein-induced transcript 3 protein

Protein Summary
Description
May be involved in hepatocellular function and development. This gene was identified due to its downregulation in hepatocarcinomas. The encoded protein may be involved in liver development and function. [provided by RefSeq, Sep 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000334011
  • ENSP00000333900
  • ENSG00000138315
  • ENST00000622652
  • ENSP00000479787

Symbol
  • LZP
  • LZP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.81
protein domain
0.73
cell type or tissue
0.41
virus perturbation
0.41
cell line
0.4


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.48   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 109   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 12.48   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 109   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (10)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
6
4
6
89.4
low density lipoprotein cholesterol measurement
2
2
3
74.1
1
1
1
47.7
red blood cell distribution width
1
1
1
42.3
serum alanine aminotransferase measurement
1
1
0
6
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
triglyceride measurement
6
89.4
low density lipoprotein cholesterol measurement
3
74.1
1
47.7
red blood cell distribution width
1
42.3
serum alanine aminotransferase measurement
0
6
33.1
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
oncoprotein induced transcript 3
736222
Macaque
oncoprotein induced transcript 3
708137
Mouse
MGI:1201782
18302
Rat
RGD:735082
294559
Horse
oncoprotein induced transcript 3
VGNC:21019
100063685
Species
Name
OMA
EggNOG
Inparanoid
Chimp
oncoprotein induced transcript 3
Macaque
oncoprotein induced transcript 3
Mouse
Rat
Horse
oncoprotein induced transcript 3
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8WWZ8-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (6)
1 – 6 of 6
MCIDAS
Tbio
Novelty:  0.01249062
Score:  0.641
Data Source:  STRINGDB
USP30
Tchem
Family:  Enzyme
Novelty:  0.03427211
Score:  0.548
Data Source:  STRINGDB
CCNJL
Tdark
Novelty:  2.86306774
Score:  0.516
Data Source:  STRINGDB
GDAP1L1
Tdark
Novelty:  0.47778991
Score:  0.44
Data Source:  STRINGDB
ABHD2
Tbio
Family:  Enzyme
Novelty:  0.05956008
Score:  0.431
Data Source:  STRINGDB
ABHD12
Tchem
Family:  Enzyme
Novelty:  0.02587535
Score:  0.41
Data Source:  STRINGDB
Publication Statistics
PubMed Score  12.48

PubMed score by year
PubTator Score  2.92

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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