LMO7
LIM domain only protein 7
Protein Summary
This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009]
- ENST00000341547
- ENSP00000342112
- ENSG00000136153
- FBX20
- FBXO20
- KIAA0858
- LOMP
- FBX20
- LMO7b
- FBXO20
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
drug perturbation | 0.96 | ||
ligand (protein) perturbation | 0.96 | ||
virus perturbation | 0.94 | ||
interacting protein | 0.76 | ||
hub protein | 0.75 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 37.18 (req: < 5)
Gene RIFs: 9 (req: <= 3)
Antibodies: 107 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 37.18 (req: >= 5)
Gene RIFs: 9 (req: > 3)
Antibodies: 107 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 9
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (380)
Nearest Tclin Targets (2)
Upstream (1)
Downstream (1)
1 – 1 of 1
Pathways (8)
Reactome (7)
KEGG (1)
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|---|
Reactome | Adaptive Immune System | ||||
Reactome | Antigen processing: Ubiquitination & Proteasome degradation | ||||
Reactome | Class I MHC mediated antigen processing & presentation | ||||
Reactome | Immune System | ||||
Reactome | Metabolism of proteins | ||||
Name | Explore in Pharos | Explore in Source | ||
|---|---|---|---|---|
Adaptive Immune System | ||||
Antigen processing: Ubiquitination & Proteasome degradation | ||||
Class I MHC mediated antigen processing & presentation | ||||
Immune System | ||||
Metabolism of proteins | ||||
Viral Interactions (0)
Gene Ontology Terms (17)
Functions (3)
Components (8)
Processes (6)
GO Term | Evidence | Assigned by | ||
|---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Disease Associations ()
GWAS Traits (5)
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|---|---|
intraocular pressure measurement | 4 | 5 | 5 | 78.5 | |||||
1 | 1 | 0 | 1.1 | 55.2 | |||||
1 | 1 | 0 | 1.4 | 46.5 | |||||
mathematical ability | 2 | 1 | 2 | 40.7 | |||||
1 | 1 | 0 | 1.1 | 31.4 | |||||
Items per page:
1 – 5 of 5
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
|---|---|---|---|---|---|---|---|
intraocular pressure measurement | 5 | 78.5 | |||||
0 | 1.1 | 55.2 | |||||
0 | 1.4 | 46.5 | |||||
mathematical ability | 2 | 40.7 | |||||
0 | 1.1 | 31.4 | |||||
Find similar targets by:
IDG Resources
Orthologs (12)
1 – 5 of 12
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|---|---|
Chimp | LIM domain 7 | VGNC:13124 | 452604 | |||||
Macaque | LIM domain 7 | 697648 | ||||||
Mouse | MGI:1353586 | 380928 | ||||||
Rat | RGD:1302984 | 361084 | ||||||
Dog | LIM domain 7 | VGNC:42725 | 476948 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
|---|---|---|---|---|---|---|
Chimp | LIM domain 7 | |||||
Macaque | LIM domain 7 | |||||
Mouse | ||||||
Rat | ||||||
Dog | LIM domain 7 | |||||
Publication Statistics
PubMed Score 37.18
PubMed score by year
PubTator Score 12.06
PubTator score by year
Related Publications
Text Mined References (27)
GeneRif Annotations (9)
Items per page:
0 of 0
PMID | Year | Title |
|---|