Tbio LMO7 LIM domain only protein 7

Protein Summary

Description

This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain, and may be involved in protein-protein interactions. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene, however, the full-length nature of some variants is not known. [provided by RefSeq, Jan 2009]

Uniprot Accession IDs

• Q8WWI1
• E9PLH4
• O15462
• O95346
• Q5TBK6
• Q9UKC1
• Q9UQM5
• Q9Y6A7
• LMO-7

Gene Name

• LMO7

Ensembl ID

• ENST00000341547
• ENSP00000342112
• ENSG00000136153

Symbol

• FBX20
• FBXO20
• KIAA0858
• LOMP
• FBX20
• LMO7b
• FBXO20

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
drug perturbation	0.96
ligand (protein) perturbation	0.96
virus perturbation	0.94
interacting protein	0.76
hub protein	0.75

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.73   (req: < 5)

Gene RIFs: 9   (req: <= 3)

Antibodies: 107   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 48.73   (req: >= 5)

Gene RIFs: 9   (req: > 3)

Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0