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Tdark
TMED6
Transmembrane emp24 domain-containing protein 6

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000288025
  • ENSP00000288025
  • ENSG00000157315

Symbol
  • p24g5
  • PRO34237
  • SPLL9146
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.98
tissue sample
0.54
cell line
0.47
virus perturbation
0.45
cellular component
0.42


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.56   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 83   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.56   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 83   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Gene Ontology Terms (9)
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (75)
1 – 10 of 75
ALG9
Tbio
Family: Enzyme
Novelty: 0.08306637
p_int: 0.998312187
p_ni: 0.001687763
p_wrong: 5e-8
Data Source: BioPlex
SMPD2
Tchem
Family: Enzyme
Novelty: 0.00474009
p_int: 0.997399201
p_ni: 0.002600772
p_wrong: 2.7e-8
Data Source: BioPlex
VEZT
Tbio
Novelty: 0.07933548
p_int: 0.997033216
p_ni: 0.00286461
p_wrong: 0.000102174
Data Source: BioPlex
LRP12
Tbio
Novelty: 0.17314548
p_int: 0.995702563
p_ni: 0.00429698
p_wrong: 4.57e-7
Data Source: BioPlex
ATP2A3
Tbio
Family: Transporter
Novelty: 0.01101086
p_int: 0.994286868
p_ni: 0.005713132
Data Source: BioPlex
ITGA2
Tbio
Novelty: 0.0018496
p_int: 0.992596317
p_ni: 0.007268902
p_wrong: 0.000134782
Data Source: BioPlex
C1QL1
Tdark
Novelty: 0.19017433
p_int: 0.983141385
p_ni: 0.016065744
p_wrong: 0.000792871
Data Source: BioPlex
BTN2A2
Tdark
Novelty: 1.22054223
p_int: 0.980513264
p_ni: 0.019486736
Data Source: BioPlex
CNTNAP3B
Tdark
Novelty: 0.3692932
p_int: 0.97915184
p_ni: 0.020848159
p_wrong: 1e-9
Data Source: BioPlex
CNNM1
Tdark
Novelty: 0.16670044
p_int: 0.97490492
p_ni: 0.023806154
p_wrong: 0.001288926
Data Source: BioPlex
Publication Statistics
PubMed Score  1.56

PubMed score by year
PubTator Score  0.71

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer