TFB1M
Dimethyladenosine transferase 1, mitochondrial
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.9 | ||
protein domain | 0.85 | ||
transcription factor perturbation | 0.74 | ||
transcription factor binding site profile | 0.71 | ||
cell type or tissue | 0.69 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism of RNA | ||||
Reactome | Mitochondrial biogenesis | ||||
Reactome | Organelle biogenesis and maintenance | ||||
Reactome | Transcriptional activation of mitochondrial biogenesis | ||||
Reactome | rRNA modification in the mitochondrion | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism of RNA | ||||
Mitochondrial biogenesis | ||||
Organelle biogenesis and maintenance | ||||
Transcriptional activation of mitochondrial biogenesis | ||||
rRNA modification in the mitochondrion | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Experiment (EXP) | Reactome | |||
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mathematical ability | 2 | 1 | 2 | 10.4 | |||||
self reported educational attainment | 1 | 1 | 1 | 10.1 | |||||
cognitive function measurement | 1 | 1 | 1 | 7.9 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mathematical ability | 2 | 10.4 | |||||
self reported educational attainment | 1 | 10.1 | |||||
cognitive function measurement | 1 | 7.9 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | transcription factor B1, mitochondrial | VGNC:12714 | 737921 | |||||
Macaque | transcription factor B1, mitochondrial | 701830 | ||||||
Mouse | MGI:2146851 | 224481 | ||||||
Rat | RGD:727795 | 308140 | ||||||
Dog | transcription factor B1, mitochondrial | VGNC:47288 | 476253 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | transcription factor B1, mitochondrial | |||||
Macaque | transcription factor B1, mitochondrial | |||||
Mouse | ||||||
Rat | ||||||
Dog | transcription factor B1, mitochondrial | |||||
PMID | Year | Title |
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