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Tdark
BCL7C
B-cell CLL/lymphoma 7 protein family member C

Protein Summary
Description
May play an anti-apoptotic role. This gene is identified by the similarity of its product to the N-terminal region of BCL7A protein. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. The function of this gene has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000215115
  • ENSP00000215115
  • ENSG00000099385
  • ENST00000380317
  • ENSP00000369674
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.87
transcription factor perturbation
0.84
kinase
0.72
transcription factor binding site profile
0.71
hub protein
0.58


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.83   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 169   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.83   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 169   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.3
55.3
comparative body size at age 10, self-reported
1
1
1
39.4
HMG CoA reductase inhibitor use measurement
1
1
1
16.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.3
55.3
comparative body size at age 10, self-reported
1
39.4
HMG CoA reductase inhibitor use measurement
1
16.2
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (69)
1 – 10 of 69
DPF3
Tbio
Family: Epigenetic
Novelty: 0.069151
p_int: 0.999999993
p_ni: 7e-9
Score: 0.877
Data Source: BioPlex,STRINGDB
PHACTR2
Tbio
Family: Enzyme
Novelty: 0.25056698
p_int: 0.99999998
p_ni: 5e-9
p_wrong: 1.5e-8
Score: 0.558
Data Source: BioPlex,STRINGDB
BRD7
Tchem
Family: Epigenetic
Novelty: 0.01820848
p_int: 0.999999973
p_ni: 2.7e-8
Score: 0.861
Data Source: BioPlex,STRINGDB
BRD9
Tchem
Family: Epigenetic
Novelty: 0.03450227
p_int: 0.999999946
p_ni: 5.2e-8
p_wrong: 1e-9
Score: 0.839
Data Source: BioPlex,STRINGDB
PHACTR4
Tbio
Family: Enzyme
Novelty: 0.11366977
p_int: 0.999999931
p_ni: 6.6e-8
p_wrong: 3e-9
Data Source: BioPlex
BICRA
Tbio
Novelty: 0.13482404
p_int: 0.999999914
p_ni: 8.6e-8
Score: 0.947
Data Source: BioPlex,STRINGDB
SMARCC2
Tbio
Family: TF; Epigenetic
Novelty: 0.02625321
p_int: 0.999999892
p_ni: 1.08e-7
Score: 0.89
Data Source: BioPlex,STRINGDB
BICRAL
Tdark
Novelty: 1.34358936
p_int: 0.999999854
p_ni: 1.46e-7
Score: 0.741
Data Source: BioPlex,STRINGDB
SMARCD1
Tbio
Novelty: 0.03176642
p_int: 0.999999848
p_ni: 1.52e-7
Score: 0.898
Data Source: BioPlex,STRINGDB
INO80
Tbio
Family: Enzyme
Novelty: 0.09412936
p_int: 0.999999285
p_ni: 7.15e-7
Score: 0.192
Data Source: BioPlex,STRINGDB
Publication Statistics
PubMed Score  2.83

PubMed score by year
PubTator Score  1.51

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer