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Tbio
GATAD1
GATA zinc finger domain-containing protein 1

Protein Summary
Description
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me). The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000287957
  • ENSP00000287957
  • ENSG00000157259

Symbol
  • ODAG
  • ODAG
  • CMD2B
  • RG083M05.2
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.91
disease perturbation
0.83
virus perturbation
0.72
cell type or tissue
0.69
histone modification site profile
0.65


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.51   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 169   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.51   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 169   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (12)
1 – 5 of 12
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
GATA zinc finger domain containing 1
VGNC:14015
746891
Macaque
GATA zinc finger domain containing 1
100427195
Mouse
MGI:1914460
67210
Rat
RGD:1562004
500005
Dog
GATA zinc finger domain containing 1
VGNC:41125
482301
Species
Name
OMA
EggNOG
Inparanoid
Chimp
GATA zinc finger domain containing 1
Macaque
GATA zinc finger domain containing 1
Mouse
Rat
Dog
GATA zinc finger domain containing 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8WUU5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (41)
1 – 10 of 41
MORF4L1
Tbio
Family: Epigenetic
Novelty: 0.01696001
p_int: 0.999995548
p_ni: 2.7e-8
p_wrong: 0.000004424
Score: 0.893
Data Source: BioPlex,STRINGDB
HDAC1
Tclin
Family: Epigenetic
Novelty: 0.00065244
p_int: 0.99998835
p_ni: 0.000003546
p_wrong: 0.000008104
Score: 0.599
Data Source: BioPlex,STRINGDB
RBBP7
Tbio
Novelty: 0.01795364
p_int: 0.999188587
p_ni: 3.9e-8
p_wrong: 0.000811375
Score: 0.799
Data Source: BioPlex,STRINGDB
PHF12
Tbio
Family: Epigenetic
Novelty: 0.00240295
Score: 0.916
Data Source: STRINGDB
KDM5A
Tchem
Family: TF; Epigenetic
Novelty: 0.00953355
Score: 0.866
Data Source: STRINGDB
SIN3B
Tbio
Novelty: 0.04097105
Score: 0.811
Data Source: STRINGDB
RBP2
Tbio
Novelty: 0.00823654
Score: 0.764
Data Source: STRINGDB
EMSY
Tbio
Novelty: 0.02216272
Score: 0.696
Data Source: STRINGDB
TMEM223
Tdark
Novelty: 0.89146194
Score: 0.692
Data Source: STRINGDB
TMEM101
Tdark
Novelty: 2.42724463
Score: 0.69
Data Source: STRINGDB
Publication Statistics
PubMed Score  13.51

PubMed score by year
PubTator Score  4.59

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer