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Tbio
UBTD2
Ubiquitin domain-containing protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000393792
  • ENSP00000377381
  • ENSG00000168246

Symbol
  • DCUBP
  • DCUBP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.85
transcription factor
0.76
transcription factor binding site profile
0.74
transcription factor perturbation
0.61
microRNA
0.56


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.17   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 160   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.17   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 160   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
2
2
2
87.8
heel bone mineral density
2
1
2
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
red blood cell distribution width
2
87.8
heel bone mineral density
2
49.5
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:2444752
327900
Rat
RGD:1305506
287178
Dog
ubiquitin domain containing 2
VGNC:48094
489120
Horse
ubiquitin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24463]
Cow
ubiquitin domain containing 2
VGNC:36621
541134
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
ubiquitin domain containing 2
Horse
ubiquitin domain containing 2 [Source:HGNC Symbol;Acc:HGNC:24463]
Cow
ubiquitin domain containing 2
Protein Structure (2 Structures, 1 AlphaFold Model)
RepresentationColor Scheme

Click on a row in the table to change the structure displayed.
More information can be found at RCSB PDB

AF-Q8WUN7-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

1 – 2 of 2
PDB Structure Id
Ligand
Method
Resolution (Å)
Residues
Fraction of Total Protein
Pub Year
Title
PDB Structure Id
Fraction of Total Protein
Resolution
Pub Year
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (30)
1 – 10 of 30
GALT
Tbio
Family:  Enzyme
Novelty:  0.0120291
p_int:  0.999999996
p_ni:  1e-9
p_wrong:  3e-9
Score:  0.261
Data Source:  BioPlex,STRINGDB
SMR3B
Tdark
Novelty:  0.0284503
p_int:  0.999979965
p_ni:  5.3e-8
p_wrong:  0.000019982
Score:  0.323
Data Source:  BioPlex,STRINGDB
CST1
Tbio
Novelty:  0.02399609
p_int:  0.999445675
p_ni:  0.000554273
p_wrong:  5.2e-8
Score:  0.235
Data Source:  BioPlex,STRINGDB
DUSP22
Tbio
Family:  Enzyme
Novelty:  0.01579003
p_int:  0.939857971
p_ni:  0.060142029
Data Source:  BioPlex
CST4
Tbio
Novelty:  0.00773554
p_int:  0.921528076
p_ni:  0.075258631
p_wrong:  0.003213293
Score:  0.238
Data Source:  BioPlex,STRINGDB
TMEM185A
Tdark
Novelty:  0.0262898
p_int:  0.909784788
p_ni:  0.090215211
p_wrong:  1e-9
Data Source:  BioPlex
PCDHGC3
Tbio
Novelty:  0.07203024
p_int:  0.906325651
p_ni:  0.093674349
Data Source:  BioPlex
GJB7
Tbio
Novelty:  0.12555147
p_int:  0.810378054
p_ni:  0.189621946
Data Source:  BioPlex
HOXB5
Tbio
Family:  TF
Novelty:  0.01119871
p_int:  0.783216732
p_ni:  0.216783268
Data Source:  BioPlex
USP5
Tchem
Family:  Enzyme
Novelty:  0.01478795
Score:  0.735
Data Source:  STRINGDB
Publication Statistics
PubMed Score  6.17

PubMed score by year
PubTator Score  3.09

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer