You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
FAM222B
Protein FAM222B

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.48   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 45   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.48   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 45   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular hemoglobin concentration
2
2
2
91.7
red blood cell distribution width
2
2
2
84.9
hemoglobin measurement
2
2
2
81.3
red blood cell density measurement
1
1
1
81.3
insomnia measurement
1
1
0
1.1
41.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular hemoglobin concentration
2
91.7
red blood cell distribution width
2
84.9
hemoglobin measurement
2
81.3
red blood cell density measurement
1
81.3
insomnia measurement
0
1.1
41.2
Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Protein-Protein Interactions (9)
1 – 9 of 9
NLK
Tchem
Family: Kinase
Novelty: 0.01512201
p_int: 0.999699398
p_ni: 8e-9
p_wrong: 0.000300595
Score: 0.439
Data Source: BioPlex,STRINGDB
NUFIP2
Tbio
Novelty: 0.09366649
Score: 0.511
Data Source: STRINGDB
BLMH
Tbio
Family: Enzyme
Novelty: 0.00855614
Score: 0.506
Data Source: STRINGDB
ZNF727
Tdark
Novelty: 4.69608864
Score: 0.491
Data Source: STRINGDB
CRYBA1
Tbio
Novelty: 0.02788955
Score: 0.457
Data Source: STRINGDB
STAMBP
Tbio
Novelty: 0.01543821
Score: 0.455
Data Source: STRINGDB
KRIT1
Tbio
Novelty: 0.00454953
Score: 0.444
Data Source: STRINGDB
PDCD10
Tbio
Novelty: 0.00683934
Score: 0.443
Data Source: STRINGDB
PHF12
Tbio
Family: Epigenetic
Novelty: 0.00240295
Score: 0.442
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.48

PubMed score by year
PubTator Score  1

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer