SCARB1
Scavenger receptor class B member 1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0.99 | ||
cellular component | 0.99 | ||
biological term | 0.98 | ||
molecular function | 0.96 | ||
disease | 0.94 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Binding and Uptake of Ligands by Scavenger Receptors | ||||
Reactome | HDL clearance | ||||
Reactome | Plasma lipoprotein assembly, remodeling, and clearance | ||||
Reactome | Plasma lipoprotein clearance | ||||
Reactome | Scavenging by Class B Receptors | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Binding and Uptake of Ligands by Scavenger Receptors | ||||
HDL clearance | ||||
Plasma lipoprotein assembly, remodeling, and clearance | ||||
Plasma lipoprotein clearance | ||||
Scavenging by Class B Receptors | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Direct Assay (IDA) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Physical Interaction (IPI) | BHF-UCL | |||
Inferred from Sequence or structural Similarity (ISS) | BHF-UCL | |||
Traceable Author Statement (TAS) | BHF-UCL | |||
Traceable Author Statement (TAS) | ARUK-UCL | |||
Traceable Author Statement (TAS) | ProtInc | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 13 | 25 | 38 | 99.5 | |||||
apolipoprotein A 1 measurement | 2 | 8 | 8 | 98.6 | |||||
sleep duration | 2 | 7 | 8 | 91.2 | |||||
5 | 4 | 5 | 1.1 | 89.7 | |||||
low density lipoprotein cholesterol measurement | 4 | 4 | 4 | 88 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
high density lipoprotein cholesterol measurement | 38 | 99.5 | |||||
apolipoprotein A 1 measurement | 8 | 98.6 | |||||
sleep duration | 8 | 91.2 | |||||
5 | 1.1 | 89.7 | |||||
low density lipoprotein cholesterol measurement | 4 | 88 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | scavenger receptor class B member 1 | VGNC:8529 | 452359 | |||||
Macaque | scavenger receptor class B member 1 | 712726 | ||||||
Mouse | MGI:893578 | 20778 | ||||||
Rat | RGD:2302 | 25073 | ||||||
Dog | scavenger receptor class B member 1 | VGNC:45898 | 486241 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | scavenger receptor class B member 1 | |||||
Macaque | scavenger receptor class B member 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | scavenger receptor class B member 1 | |||||
PMID | Year | Title |
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