PARD3
Partitioning defective 3 homolog
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.96 | ||
virus perturbation | 0.88 | ||
biological process | 0.87 | ||
drug perturbation | 0.87 | ||
PubMedID | 0.83 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Cell junction organization | ||||
Reactome | Cell-Cell communication | ||||
Reactome | Cell-cell junction organization | ||||
Reactome | Signal Transduction | ||||
Reactome | Signaling by TGF-beta Receptor Complex | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Cell junction organization | ||||
Cell-Cell communication | ||||
Cell-cell junction organization | ||||
Signal Transduction | ||||
Signaling by TGF-beta Receptor Complex | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mathematical ability | 3 | 2 | 3 | 71.4 | |||||
serum gamma-glutamyl transferase measurement | 1 | 1 | 1 | 70.9 | |||||
self reported educational attainment | 1 | 1 | 1 | 54.4 | |||||
FEV/FEC ratio | 1 | 1 | 1 | 51.7 | |||||
glomerular filtration rate | 2 | 2 | 1 | 5.7 | 48.5 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mathematical ability | 3 | 71.4 | |||||
serum gamma-glutamyl transferase measurement | 1 | 70.9 | |||||
self reported educational attainment | 1 | 54.4 | |||||
FEV/FEC ratio | 1 | 51.7 | |||||
glomerular filtration rate | 1 | 5.7 | 48.5 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | par-3 family cell polarity regulator | VGNC:7854 | 450398 | |||||
Macaque | par-3 family cell polarity regulator | 706472 | ||||||
Mouse | MGI:2135608 | 93742 | ||||||
Rat | RGD:620374 | 81918 | ||||||
Dog | par-3 family cell polarity regulator | VGNC:44263 | 477953 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | par-3 family cell polarity regulator | |||||
Macaque | par-3 family cell polarity regulator | |||||
Mouse | ||||||
Rat | ||||||
Dog | par-3 family cell polarity regulator | |||||
PMID | Year | Title |
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