DENND1A
DENN domain-containing protein 1A
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.8 | ||
phenotype | 0.79 | ||
transcription factor | 0.79 | ||
drug perturbation | 0.71 | ||
cellular component | 0.68 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Membrane Trafficking | ||||
Reactome | RAB GEFs exchange GTP for GDP on RABs | ||||
Reactome | Rab regulation of trafficking | ||||
Reactome | Vesicle-mediated transport | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Membrane Trafficking | ||||
RAB GEFs exchange GTP for GDP on RABs | ||||
Rab regulation of trafficking | ||||
Vesicle-mediated transport | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
3 | 3 | 1 | 1.4 | 86.8 | |||||
hair color | 1 | 1 | 0 | 1.1 | 85.7 | ||||
risk-taking behaviour | 3 | 3 | 3 | 1 | 79.4 | ||||
body mass index | 4 | 4 | 5 | 75.6 | |||||
self reported educational attainment | 1 | 2 | 2 | 72.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
1 | 1.4 | 86.8 | |||||
hair color | 0 | 1.1 | 85.7 | ||||
risk-taking behaviour | 3 | 1 | 79.4 | ||||
body mass index | 5 | 75.6 | |||||
self reported educational attainment | 2 | 72.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | DENN domain containing 1A | VGNC:4672 | 473055 | |||||
Macaque | DENN domain containing 1A | 698028 | ||||||
Mouse | MGI:2442794 | 227801 | ||||||
Rat | RGD:1307927 | 311913 | ||||||
Dog | DENN domain containing 1A | VGNC:39884 | 609706 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | DENN domain containing 1A | |||||
Macaque | DENN domain containing 1A | |||||
Mouse | ||||||
Rat | ||||||
Dog | DENN domain containing 1A | |||||
PMID | Year | Title |
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