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Tdark
C10orf105
Uncharacterized protein C10orf105

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000398786
  • ENSP00000381766
  • ENSG00000214688
  • ENST00000441508
  • ENSP00000403151
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.17   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.17   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (13)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
1
3
85.7
leukocyte count
3
2
4
81.6
myeloid white cell count
3
1
3
80.9
monocyte count
2
1
2
77.7
neutrophil count
2
1
2
74.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
lymphocyte count
3
85.7
leukocyte count
4
81.6
myeloid white cell count
3
80.9
monocyte count
2
77.7
neutrophil count
2
74.8
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:4937089
100302688
Rat
RGD:2320942
100361018
Dog
chromosome 4 C10orf105 homolog
VGNC:49199
102152745
Cow
chromosome 28 C10orf105 homolog
VGNC:52694
101904363
Anole lizard
chromosome 10 open reading frame 105 [Source:HGNC Symbol;Acc:HGNC:20304]
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
chromosome 4 C10orf105 homolog
Cow
chromosome 28 C10orf105 homolog
Anole lizard
chromosome 10 open reading frame 105 [Source:HGNC Symbol;Acc:HGNC:20304]
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8TEF2-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (1)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (7)
1 – 7 of 7
SNHG28
Tdark
Novelty:  1.12069377
Score:  0.564
Data Source:  STRINGDB
VSIG8
Tdark
Novelty:  1.16023405
Score:  0.559
Data Source:  STRINGDB
RNF39
Tbio
Novelty:  0.0340178
Score:  0.513
Data Source:  STRINGDB
PRRT1
Tbio
Novelty:  0.08707857
Score:  0.511
Data Source:  STRINGDB
FRMD4B
Tbio
Novelty:  0.20691438
Score:  0.511
Data Source:  STRINGDB
EGFL8
Tbio
Novelty:  0.01309625
Score:  0.51
Data Source:  STRINGDB
PPT2
Tbio
Family:  Enzyme
Novelty:  0.00829249
Score:  0.429
Data Source:  STRINGDB
Publication Statistics
PubMed Score  0.17

PubMed score by year
PubTator Score  0.17

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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