Tbio GPX8 Probable glutathione peroxidase 8

Protein Summary

Uniprot Accession IDs

• Q8TED1
• GPx-8

Gene Name

• GPX8

Ensembl ID

• ENST00000503787
• ENSP00000423822
• ENSG00000164294

Symbol

• GPx-8
• UNQ847
• EPLA847
• GSHPx-8

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor perturbation	0.88
virus perturbation	0.85
small molecule perturbation	0.79
kinase perturbation	0.66
tissue sample	0.59

Protein Classes

PANTHER Classes

Protein / Oxidoreductase / Peroxidase / Probable Glutathione Peroxidase 8

DTO Classes

Protein / Enzyme / Oxidoreductase / Peroxidase / Probable Glutathione Peroxidase 8

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 54.21   (req: < 5)

Gene RIFs: 13   (req: <= 3)

Antibodies: 107   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 54.21   (req: >= 5)

Gene RIFs: 13   (req: > 3)

Antibodies: 107   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0