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Tbio
TAS1R2
Taste receptor type 1 member 2

Protein Classes
Protein Summary
Description
Putative taste receptor. TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000375371
  • ENSP00000364520
  • ENSG00000179002

Symbol
  • GPR71
  • T1R2
  • TR2
  • TR2
  • T1R2
  • GPR71
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
tissue
0.71
tissue sample
0.71
cell type or tissue
0.56
cell line
0.5


Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 176.62   (req: < 5)
Gene RIFs: 24   (req: <= 3)
Antibodies: 185   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 176.62   (req: >= 5)
Gene RIFs: 24   (req: > 3)
Antibodies: 185   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
taste 1 receptor member 2
VGNC:53216
100615078
Macaque
taste 1 receptor member 2
714666
Mouse
MGI:1933546
83770
Cow
taste 1 receptor member 2
VGNC:35608
529847
Opossum
taste 1 receptor member 2
100619414
Species
Name
OMA
EggNOG
Inparanoid
Chimp
taste 1 receptor member 2
Macaque
taste 1 receptor member 2
Mouse
Cow
taste 1 receptor member 2
Opossum
taste 1 receptor member 2
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8TE23-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (8)
Class C/3 (Metabotropic glutamate/pheromone receptors) (R-HSA-420499)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 6
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Class C/3 (Metabotropic glutamate/pheromone receptors)
Reactome
G alpha (i) signalling events
Reactome
GPCR downstream signalling
Reactome
GPCR ligand binding
Reactome
Signal Transduction
Name
Explore in Pharos
Explore in Source
Class C/3 (Metabotropic glutamate/pheromone receptors)
G alpha (i) signalling events
GPCR downstream signalling
GPCR ligand binding
Signal Transduction
Protein-Protein Interactions (273)
1 – 10 of 273
GNAT3
Tbio
Novelty:  0.00702357
Score:  0.99
Data Source:  STRINGDB
TAS2R13
Tchem
Family:  GPCR
Novelty:  0.25394315
Score:  0.971
Data Source:  STRINGDB
TAS2R38
Tchem
Family:  GPCR
Novelty:  0.004625
Score:  0.971
Data Source:  STRINGDB
TAS2R4
Tchem
Family:  GPCR
Novelty:  0.02938385
Score:  0.968
Data Source:  STRINGDB
TAS2R5
Tchem
Family:  GPCR
Novelty:  0.08512891
Score:  0.967
Data Source:  STRINGDB
TAS2R1
Tchem
Family:  GPCR
Novelty:  0.04676914
Score:  0.964
Data Source:  STRINGDB
TAS2R9
Tchem
Family:  GPCR
Novelty:  0.27583951
Score:  0.964
Data Source:  STRINGDB
TAS2R10
Tchem
Family:  GPCR
Novelty:  0.07564224
Score:  0.961
Data Source:  STRINGDB
TAS2R3
Tchem
Family:  GPCR
Novelty:  0.09368884
Score:  0.959
Data Source:  STRINGDB
PYY
Tbio
Novelty:  0.00060997
Score:  0.958
Data Source:  STRINGDB
Publication Statistics
PubMed Score  176.62

PubMed score by year
PubTator Score  74.1

PubTator score by year
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer