PANK1
Pantothenate kinase 1
You are using an outdated browser. Please upgrade your browser to improve your experience.
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.91 | ||
molecular function | 0.88 | ||
kinase perturbation | 0.84 | ||
transcription factor binding site profile | 0.84 | ||
microRNA | 0.83 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
Click on a row in the table to change the structure displayed.
Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Coenzyme A biosynthesis | ||||
Reactome | Metabolism | ||||
Reactome | Metabolism of vitamins and cofactors | ||||
Reactome | Metabolism of water-soluble vitamins and cofactors | ||||
Reactome | Vitamin B5 (pantothenate) metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Coenzyme A biosynthesis | ||||
Metabolism | ||||
Metabolism of vitamins and cofactors | ||||
Metabolism of water-soluble vitamins and cofactors | ||||
Vitamin B5 (pantothenate) metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Direct Assay (IDA) | UniProtKB | |||
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mathematical ability | 3 | 3 | 4 | 57.1 | |||||
hematocrit | 1 | 1 | 1 | 50.6 | |||||
platelet crit | 1 | 1 | 1 | 38.2 | |||||
electrocardiography | 1 | 1 | 6 | 33.1 | |||||
mean corpuscular volume | 1 | 1 | 1 | 31.4 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mathematical ability | 4 | 57.1 | |||||
hematocrit | 1 | 50.6 | |||||
platelet crit | 1 | 38.2 | |||||
electrocardiography | 6 | 33.1 | |||||
mean corpuscular volume | 1 | 31.4 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | pantothenate kinase 1 | VGNC:12414 | 450590 | |||||
Macaque | pantothenate kinase 1 | 696041 | ||||||
Mouse | MGI:1922985 | 75735 | ||||||
Dog | pantothenate kinase 1 | 486790 | ||||||
Cow | pantothenate kinase 1 | VGNC:32563 | 535887 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | pantothenate kinase 1 | |||||
Macaque | pantothenate kinase 1 | |||||
Mouse | ||||||
Dog | pantothenate kinase 1 | |||||
Cow | pantothenate kinase 1 | |||||
PMID | Year | Title |
---|