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Tchem
OXER1
Oxoeicosanoid receptor 1

Protein Summary
Description
Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000378661
  • ENSP00000367930
  • ENSG00000162881

Symbol
  • GPR170
  • TG1019
  • GPCR
  • GPR170
  • TG1019
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.76
tissue sample
0.66
cell type or tissue
0.56
ligand (chemical)
0.51
pathway
0.47


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.18   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 226   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 32.18   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 226   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligands: 30
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0