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Tbio
CALML6
Calmodulin-like protein 6

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.8   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 98   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.8   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 98   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (107)
Items per page:
1 – 5 of 40
Data Source
Name
Explore in Pharos
Explore in Source
KEGG
Inflammatory mediator regulation of TRP channels
KEGG
Aldosterone synthesis and secretion
KEGG
Oxytocin signaling pathway
KEGG
Kaposi sarcoma-associated herpesvirus infection
KEGG
Gastric acid secretion
Name
Explore in Pharos
Explore in Source
Inflammatory mediator regulation of TRP channels
Aldosterone synthesis and secretion
Oxytocin signaling pathway
Kaposi sarcoma-associated herpesvirus infection
Gastric acid secretion
Gene Ontology Terms (6)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (116)
1 – 10 of 116
CAMKK2
Tchem
Family: Kinase
Novelty: 0.00426898
Score: 0.88
Data Source: STRINGDB
CAMK4
Tbio
Family: Kinase
Novelty: 0.00412444
Score: 0.864
Data Source: STRINGDB
NOS3
Tchem
Family: Enzyme
Novelty: 0.00012407
Score: 0.855
Data Source: STRINGDB
NOS1
Tchem
Family: Enzyme
Novelty: 0.00032064
Score: 0.855
Data Source: STRINGDB
CACNA1C
Tclin
Family: IC
Novelty: 0.00099998
Score: 0.853
Data Source: STRINGDB
PHKG1
Tchem
Family: Kinase
Novelty: 0.08576384
Score: 0.837
Data Source: STRINGDB
HSP90AB1
Tchem
Novelty: 0.00907961
Score: 0.834
Data Source: STRINGDB
HSP90AA1
Tchem
Novelty: 0.00016774
Score: 0.834
Data Source: STRINGDB
PHKG2
Tchem
Family: Kinase
Novelty: 0.064884
Score: 0.827
Data Source: STRINGDB
HSP90B1
Tchem
Novelty: 0.00135881
Score: 0.822
Data Source: STRINGDB
Publication Statistics
PubMed Score  5.80

PubMed score by year
PubTator Score  6.33

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer