Tbio RHPN1 Rhophilin-1

Protein Summary

Description

Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.

Uniprot Accession IDs

• Q8TCX5
• Q8TAV1
• Q96PV9

Gene Name

• RHPN1

Ensembl ID

• ENST00000289013
• ENSP00000289013
• ENSG00000158106

Symbol

• KIAA1929
• ODF5
• RHPN
• RHOPHILIN

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.84
cell line	0.53
gene perturbation	0.52
metabolite	0.45
cell type or tissue	0.44

Protein Classes

PANTHER Classes

Protein / Enzyme Modulator / G-protein Modulator / Rhophilin-1

DTO Classes

Protein / Enzyme Modulator / G-protein Modulator / Rhophilin-1

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.07   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 156   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 15.07   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 156   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0