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Tdark
SLC7A13
Solute carrier family 7 member 13

Protein Summary
Description
Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000297524
  • ENSP00000297524
  • ENSG00000164893
  • ENST00000419776
  • ENSP00000410982

Symbol
  • AGT1
  • XAT2
  • AGT1
  • XAT2
  • AGT-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.68
cell type or tissue
0.46
metabolite
0.45
virus perturbation
0.45
phenotype
0.43


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.99   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 6   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.99   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 6   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
RESOLUTE
Thumbnail image for RESOLUTE
RESOLUTE is a public-private partnership with the goal of escalating research on solute carriers (SLCs) and to establish SLCs as a tractable target class for medical research and development.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (50)
1 – 10 of 50
SLCO4C1
Tchem
Family:  Transporter
Novelty:  0.04138167
Score:  0.727
Data Source:  STRINGDB
SLC7A3
Tbio
Family:  Transporter
Novelty:  0.00779949
Score:  0.715
Data Source:  STRINGDB
SLC22A31
Tdark
Family:  Transporter
Novelty:  1.20015654
Score:  0.71
Data Source:  STRINGDB
SLCO3A1
Tbio
Family:  Transporter
Novelty:  0.03629339
Score:  0.705
Data Source:  STRINGDB
SLCO4A1
Tbio
Family:  Transporter
Novelty:  0.01617036
Score:  0.688
Data Source:  STRINGDB
SLCO2A1
Tchem
Family:  Transporter
Novelty:  0.00133475
Score:  0.672
Data Source:  STRINGDB
SLC22A6
Tclin
Family:  Transporter
Novelty:  0.00389149
Score:  0.649
Data Source:  STRINGDB
SLCO1B7
Tdark
Family:  Transporter
Novelty:  0.48557976
Score:  0.642
Data Source:  STRINGDB
SLC22A10
Tdark
Family:  Transporter
Novelty:  0.06167295
Score:  0.633
Data Source:  STRINGDB
SLC22A11
Tclin
Family:  Transporter
Novelty:  0.01343595
Score:  0.632
Data Source:  STRINGDB
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
1
3
3
94.9
glomerular filtration rate
2
2
2
78.7
self reported educational attainment
1
2
2
57.8
mathematical ability
1
2
2
53.2
low density lipoprotein cholesterol measurement
1
1
1
33.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
total cholesterol measurement
3
94.9
glomerular filtration rate
2
78.7
self reported educational attainment
2
57.8
mathematical ability
2
53.2
low density lipoprotein cholesterol measurement
1
33.1
Find similar targets by:
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 7 member 13
VGNC:14591
735712
Macaque
solute carrier family 7 member 13 [Source:HGNC Symbol;Acc:HGNC:23092]
Mouse
MGI:1921337
74087
Rat
RGD:1311633
313089
Horse
solute carrier family 7 member 13
VGNC:23268
100055860
Species
Name
OMA
EggNOG
Inparanoid
Chimp
solute carrier family 7 member 13
Macaque
solute carrier family 7 member 13 [Source:HGNC Symbol;Acc:HGNC:23092]
Mouse
Rat
Horse
solute carrier family 7 member 13
Publication Statistics
PubMed Score 3.99
PubMed score by year
PubTator Score 10.65
PubTator score by year