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Tdark
C18orf32
UPF0729 protein C18orf32

Protein Summary
Description
May activate the NF-kappa-B signaling pathway.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000318240
  • ENSP00000323199
  • ENSG00000177576
  • ENST00000582392
  • ENSP00000462538
  • ENST00000613385
  • ENSP00000480941
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0
biological term
0
cell line
0
cell type or tissue
0
cellular component
0


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.67   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 32   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.67   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 32   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (266)
P62861
Tbio
Novelty:  0.01170009
Score:  0.971
Data Source:  STRINGDB
P35544
Tbio
Novelty:  0.01170009
Score:  0.971
Data Source:  STRINGDB
RPL37A
Tbio
Novelty:  0.03475061
Score:  0.961
Data Source:  STRINGDB
RPS4X
Tbio
Novelty:  0.01396038
Score:  0.957
Data Source:  STRINGDB
RPL9
Tbio
Novelty:  0.00845583
Score:  0.952
Data Source:  STRINGDB
RPL31
Tbio
Novelty:  0.03427872
Score:  0.951
Data Source:  STRINGDB
RPL35
Tbio
Novelty:  0.03722634
Score:  0.949
Data Source:  STRINGDB
RPS15
Tbio
Novelty:  0.00635155
Score:  0.948
Data Source:  STRINGDB
RPS3
Tbio
Novelty:  0.003106
Score:  0.947
Data Source:  STRINGDB
RPL36
Tbio
Novelty:  0.02259932
Score:  0.946
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (19)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
12
8
18
5
99.6
apolipoprotein A 1 measurement
2
5
6
98.9
total cholesterol measurement
4
4
9
98.1
BMI-adjusted hip circumference
2
9
12
93
body height
1
1
1
76.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
high density lipoprotein cholesterol measurement
18
5
99.6
apolipoprotein A 1 measurement
6
98.9
total cholesterol measurement
9
98.1
BMI-adjusted hip circumference
12
93
body height
1
76.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
chromosome 18 C18orf32 homolog
VGNC:13243
100612211
Mouse
MGI:3039614
407819
Rat
RGD:1562987
498886
Dog
chromosome 7 C18orf32 homolog
VGNC:52584
100688326
Cow
chromosome 24 C18orf32 homolog
VGNC:52682
767921
Species
Name
OMA
EggNOG
Inparanoid
Chimp
chromosome 18 C18orf32 homolog
Mouse
Rat
Dog
chromosome 7 C18orf32 homolog
Cow
chromosome 24 C18orf32 homolog
Publication Statistics
PubMed Score 0.67
PubMed score by year
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Related Publications
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PMID
Year
Title