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Tbio
IFI44
Interferon-induced protein 44

Protein Summary
Description
This protein aggregates to form microtubular structures.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000370747
  • ENSP00000359783
  • ENSG00000137965

Symbol
  • MTAP44
  • p44
  • TLDC5
  • MTAP44
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
1
gene perturbation
0.96
transcription factor perturbation
0.94
PubMedID
0.65
tissue
0.62


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.29   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 130   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 33.29   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 130   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
MMR-related febrile seizures
1
1
0
1.4
52.4
Febrile seizure (within the age range of 3 months to 6 years)
1
1
0
1.4
35
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
MMR-related febrile seizures
0
1.4
52.4
Febrile seizure (within the age range of 3 months to 6 years)
0
1.4
35
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
interferon induced protein 44
VGNC:6881
456971
Mouse
MGI:2443016
99899
Rat
RGD:1310523
310969
Dog
interferon induced protein 44
VGNC:41873
490198
Cow
interferon induced protein 44
VGNC:30045
508348
Species
Name
OMA
EggNOG
Inparanoid
Chimp
interferon induced protein 44
Mouse
Rat
Dog
interferon induced protein 44
Cow
interferon induced protein 44
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8TCB0-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (4)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Protein-Protein Interactions (71)
1 – 10 of 71
IFNA21
Tbio
Novelty:  0.00581034
p_int:  0.999941587
p_ni:  6e-8
p_wrong:  0.000058353
Score:  0.378
Data Source:  BioPlex,STRINGDB
IFIT1
Tbio
Novelty:  0.00562299
Score:  0.961
Data Source:  STRINGDB
IFIT3
Tbio
Novelty:  0.00568113
Score:  0.95
Data Source:  STRINGDB
ISG15
Tbio
Novelty:  0.00203781
Score:  0.949
Data Source:  STRINGDB
MX1
Tbio
Novelty:  0.00072554
Score:  0.947
Data Source:  STRINGDB
RSAD2
Tbio
Novelty:  0.0056473
Score:  0.942
Data Source:  STRINGDB
IFI6
Tbio
Novelty:  0.02590679
Score:  0.94
Data Source:  STRINGDB
OAS1
Tbio
Family:  Enzyme
Novelty:  0.00532331
Score:  0.937
Data Source:  STRINGDB
IFIT2
Tbio
Novelty:  0.01023074
Score:  0.933
Data Source:  STRINGDB
OAS2
Tbio
Family:  Enzyme
Novelty:  0.01673393
Score:  0.927
Data Source:  STRINGDB
Publication Statistics
PubMed Score  33.29

PubMed score by year
PubTator Score  447.57

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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