RDH11
Retinol dehydrogenase 11
Protein Summary
Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity towards 9-cis and all-trans-retinol. Also involved in the metabolism of short-chain aldehydes. No steroid dehydrogenase activity detected. The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity. [provided by RefSeq, Nov 2011]
- ENST00000381346
- ENSP00000370750
- ENSG00000072042
- ENST00000428130
- ENSP00000416395
- ENST00000553384
- ENSP00000452079
- ARSDR1
- PSDR1
- SDR7C1
- MDT1
- CGI82
- PSDR1
- RALR1
- SCALD
- ARSDR1
- HCBP12
- RDJCSS
- SDR7C1
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
transcription factor perturbation | 0.97 | ||
disease perturbation | 0.95 | ||
kinase perturbation | 0.81 | ||
microRNA | 0.74 | ||
cellular component | 0.73 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 51.72 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 212 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 51.72 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 212 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0