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Tdark
TMEM167A
Protein kish-A

Protein Summary
Description
Involved in the early part of the secretory pathway.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000502346
  • ENSP00000424707
  • ENSG00000174695

Symbol
  • TMEM167
  • TMEM167
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.96
histone modification site profile
0.89
kinase perturbation
0.84
microRNA
0.83
virus perturbation
0.72


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.37   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.37   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (17)
1 – 10 of 17
YIPF5
Tbio
Novelty:  0.08206828
Score:  0.709
Data Source:  STRINGDB
IER3IP1
Tbio
Novelty:  0.07401881
Score:  0.704
Data Source:  STRINGDB
TAF9
Tbio
Score:  0.685
Data Source:  STRINGDB
HAT1
Tbio
Family:  Epigenetic
Novelty:  0.03621612
Score:  0.68
Data Source:  STRINGDB
TXNDC9
Tbio
Novelty:  0.00309772
Score:  0.665
Data Source:  STRINGDB
ZBED4
Tdark
Family:  TF
Novelty:  0.33487119
Score:  0.651
Data Source:  STRINGDB
MCTS1
Tbio
Novelty:  0.07039427
Score:  0.65
Data Source:  STRINGDB
NUDCD2
Tdark
Novelty:  0.60015068
Score:  0.56
Data Source:  STRINGDB
ERGIC2
Tbio
Novelty:  0.08610944
Score:  0.556
Data Source:  STRINGDB
TVP23B
Tdark
Novelty:  0.62740035
Score:  0.533
Data Source:  STRINGDB
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
2
2
58.2
cortical surface area measurement
1
1
0
2.7
29
balding measurement
1
1
1
11
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
heel bone mineral density
2
58.2
cortical surface area measurement
0
2.7
29
balding measurement
1
11
Find similar targets by:
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1913324
66074
Rat
RGD:2323318
100359823
Dog
transmembrane protein 167A
VGNC:47493
610083
Horse
transmembrane protein 167A
VGNC:24215
100629746
Cow
transmembrane protein 167A
VGNC:35991
613669
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
transmembrane protein 167A
Horse
transmembrane protein 167A
Cow
transmembrane protein 167A
Publication Statistics
PubMed Score 1.37
PubMed score by year