Tbio TBC1D16 TBC1 domain family member 16

Protein Summary

Description

May act as a GTPase-activating protein for Rab family protein(s).

Uniprot Accession IDs

• Q8TBP0
• B9A6L7
• I3L1E0
• I3L4U2
• Q8N3Z4
• Q96DH7

Gene Name

• TBC1D16

Ensembl ID

• ENST00000310924
• ENSP00000309794
• ENSG00000167291
• ENST00000340848
• ENSP00000341517
• ENST00000572862
• ENSP00000458766
• ENST00000576768
• ENSP00000461522

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.83
cell line	0.7
tissue	0.67
transcription factor binding site profile	0.67
tissue sample	0.58

Protein Classes

PANTHER Classes

Protein / Hydrolase / Tbc1 Domain Family Member 16

Protein / Enzyme Modulator / G-protein Modulator / Tbc1 Domain Family Member 16

Protein / ... / Cysteine Protease / Tbc1 Domain Family Member 16

DTO Classes

Protein / Enzyme / Protease / Cysteine Protease / Tbc1 Domain Family Member 16

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.75   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 65   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.75   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 65   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0