Tbio ETNPPL Ethanolamine-phosphate phospho-lyase

Protein Summary

Description

Catalyzes the pyridoxal-phosphate-dependent breakdown of phosphoethanolamine, converting it to ammonia, inorganic phosphate and acetaldehyde.

Uniprot Accession IDs

• Q8TBG4
• B7Z1Y0
• E9PBY0
• Q9H174

Gene Name

• ETNPPL

Ensembl ID

• ENST00000296486
• ENSP00000296486
• ENSG00000164089
• ENST00000411864
• ENSP00000392269
• ENST00000512646
• ENSP00000427065

Symbol

• AGXT2L1
• AGXT2L1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
gene perturbation	0.76
histone modification site profile	0.72
cell type or tissue	0.63
protein domain	0.58
molecular function	0.56

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.32   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 50   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14.32   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 50   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0