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Tdark
ZNF519
Zinc finger protein 519

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000590202
  • ENSP00000464872
  • ENSG00000175322

Symbol
  • HsT2362
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.8
histone modification site profile
0.77
microRNA
0.66
virus perturbation
0.64
protein domain
0.58


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.24   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 27   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.24   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 27   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
ocular sarcoidosis
1
1
0
2.5
38.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
ocular sarcoidosis
0
2.5
38.8
Orthologs (1)
1 – 1 of 1
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 519
VGNC:7823
468598
Species
Name
OMA
EggNOG
Inparanoid
Chimp
zinc finger protein 519
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8TB69-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (4)
Gene expression (Transcription) (R-HSA-74160)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Gene expression (Transcription)
Reactome
Generic Transcription Pathway
Reactome
RNA Polymerase II Transcription
Name
Explore in Pharos
Explore in Source
Gene expression (Transcription)
Generic Transcription Pathway
RNA Polymerase II Transcription
Protein-Protein Interactions (8)
1 – 8 of 8
TRIM28
Tbio
Family:  Epigenetic
Novelty:  0.00778381
Score:  0.933
Data Source:  STRINGDB
FAM174A
Tdark
Novelty:  0.30693139
Score:  0.54
Data Source:  STRINGDB
CCDC178
Tdark
Novelty:  0.59356582
Score:  0.477
Data Source:  STRINGDB
PCDHB11
Tdark
Novelty:  0.80480462
Score:  0.452
Data Source:  STRINGDB
SLFN13
Tdark
Novelty:  0.37102263
Score:  0.443
Data Source:  STRINGDB
ARL17A
Tdark
Family:  Enzyme
Novelty:  0.37276049
Score:  0.433
Data Source:  STRINGDB
ARGLU1
Tdark
Novelty:  0.28840832
Score:  0.426
Data Source:  STRINGDB
DYM
Tbio
Novelty:  0.02348265
Score:  0.41
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.24

PubMed score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer