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Tbio
LMO3
LIM domain only protein 3

Protein Summary
Description
The protein encoded by this gene belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. This gene is predominantly expressed in the brain. Related family members, LMO1 and LMO2 on chromosome 11, have been reported to be involved in chromosomal translocations in T-cell leukemia. Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000261169
  • ENSP00000261169
  • ENSG00000048540
  • ENST00000320122
  • ENSP00000312856
  • ENST00000354662
  • ENSP00000346689
  • ENST00000441439
  • ENSP00000412479
  • ENST00000447609
  • ENSP00000413703
  • ENST00000534946
  • ENSP00000439275
  • ENST00000535535
  • ENSP00000446115
  • ENST00000537304
  • ENSP00000440099
  • ENST00000540445
  • ENSP00000442786
  • ENST00000540848
  • ENSP00000445751
  • ENST00000541295
  • ENSP00000446463
  • ENST00000541846
  • ENSP00000444393

Symbol
  • RBTN3
  • RBTNL2
  • RHOM3
  • RBTN3
  • RHOM3
  • RBTNL2
  • Rhom-3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.66
transcription factor
0.65
tissue sample
0.64
cell line
0.59
microRNA
0.59


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.56   (req: < 5)
Gene RIFs: 17   (req: <= 3)
Antibodies: 255   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 39.56   (req: >= 5)
Gene RIFs: 17   (req: > 3)
Antibodies: 255   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0