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Tbio
ERMN
Ermin

Protein Summary
Description
Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000397283
  • ENSP00000380453
  • ENSG00000136541
  • ENST00000410096
  • ENSP00000387047

Symbol
  • KIAA1189
  • JN
  • KIAA1189
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.73
gene perturbation
0.71
microRNA
0.62
cellular component
0.51
tissue
0.46


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.2   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 93   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 24.2   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 93   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (71)
1 – 10 of 71
SULT4A1
Tbio
Family:  Enzyme
Novelty:  0.02455678
p_int:  0.977977322
p_ni:  0.022016576
p_wrong:  0.000006101
Score:  0.722
Data Source:  BioPlex,STRINGDB
OPALIN
Tdark
Novelty:  0.08221612
Score:  0.82
Data Source:  STRINGDB
RPL8
Tbio
Novelty:  0.01064076
Score:  0.755
Data Source:  STRINGDB
FAM216B
Tdark
Novelty:  4.08033007
Score:  0.746
Data Source:  STRINGDB
TTYH2
Tbio
Family:  IC
Novelty:  0.19796461
Score:  0.729
Data Source:  STRINGDB
MOBP
Tbio
Novelty:  0.01761387
Score:  0.702
Data Source:  STRINGDB
EFHD1
Tbio
Novelty:  0.00808906
Score:  0.698
Data Source:  STRINGDB
RDX
Tbio
Novelty:  0.00236103
Score:  0.645
Data Source:  STRINGDB
MSN
Tbio
Novelty:  0.00178275
Score:  0.641
Data Source:  STRINGDB
KNDC1
Tdark
Novelty:  0.1459108
Score:  0.615
Data Source:  STRINGDB
Gene Ontology Terms (14)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
Ensembl
Orthologs (8)
1 – 5 of 8
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ermin
VGNC:416
459672
Mouse
MGI:1925017
77767
Rat
RGD:1308367
295619
Dog
ermin
VGNC:40462
607626
Horse
ermin
VGNC:17672
100059459
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ermin
Mouse
Rat
Dog
ermin
Horse
ermin
Publication Statistics
PubMed Score 24.20
PubMed score by year
PubTator Score 5.34
PubTator score by year