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Tbio
OLIG1
Oligodendrocyte transcription factor 1

Protein Summary
Description
Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000382348
  • ENSP00000371785
  • ENSG00000184221

Symbol
  • BHLHB6
  • BHLHE21
  • BHLHB6
  • BHLHE21
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.65
gene perturbation
0.64
PubMedID
0.64
microRNA
0.49
biological process
0.45


Related Tools
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.93   (req: < 5)
Gene RIFs: 12   (req: <= 3)
Antibodies: 306   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 94.93   (req: >= 5)
Gene RIFs: 12   (req: > 3)
Antibodies: 306   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
oligodendrocyte transcription factor 1
706574
Mouse
MGI:1355334
50914
Rat
RGD:621129
60394
Dog
oligodendrocyte transcription factor 1
VGNC:53034
487736
Cow
oligodendrocyte transcription factor 1
VGNC:32425
539307
Species
Name
OMA
EggNOG
Inparanoid
Macaque
oligodendrocyte transcription factor 1
Mouse
Rat
Dog
oligodendrocyte transcription factor 1
Cow
oligodendrocyte transcription factor 1
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8TAK6-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Protein-Protein Interactions (73)
1 – 10 of 73
ID4
Tbio
Family: TF
Novelty: 0.00399089
Score: 0.88
Data Source: STRINGDB
SOX10
Tbio
Family: TF
Novelty: 0.00130552
Score: 0.799
Data Source: STRINGDB
NKX2-2
Tbio
Family: TF
Novelty: 0.00608835
Score: 0.776
Data Source: STRINGDB
MBP
Tbio
Novelty: 0.00016333
Score: 0.762
Data Source: STRINGDB
GFAP
Tbio
Novelty: 0.00020932
Score: 0.753
Data Source: STRINGDB
CCNDBP1
Tbio
Novelty: 0.01527762
Score: 0.736
Data Source: STRINGDB
ID2
Tbio
Family: TF
Novelty: 0.00256364
Score: 0.736
Data Source: STRINGDB
MAG
Tchem
Novelty: 0.00085621
Score: 0.706
Data Source: STRINGDB
GPR17
Tchem
Family: GPCR
Novelty: 0.00545502
Score: 0.704
Data Source: STRINGDB
PLP1
Tbio
Novelty: 0.00129083
Score: 0.683
Data Source: STRINGDB
Publication Statistics
PubMed Score  94.93

PubMed score by year
PubTator Score  61.96

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer