TPCN2
Two pore calcium channel protein 2
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
molecular function | 0.96 | ||
cell line | 0.59 | ||
cellular component | 0.56 | ||
histone modification site profile | 0.56 | ||
biological process | 0.55 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Ion channel transport | ||||
Reactome | Stimuli-sensing channels | ||||
Reactome | Transport of small molecules | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Ion channel transport | ||||
Stimuli-sensing channels | ||||
Transport of small molecules | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | IntAct | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Sequence or structural Similarity (ISS) | UniProtKB | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
hair color | 6 | 7 | 0 | 1.6 | 99.6 | ||||
12 | 8 | 1 | 1.2 | 98.1 | |||||
heel bone mineral density | 3 | 2 | 6 | 93.7 | |||||
hair colour measurement | 1 | 1 | 1 | 87.2 | |||||
BMI-adjusted hip circumference | 2 | 9 | 10 | 84.1 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
hair color | 0 | 1.6 | 99.6 | ||||
1 | 1.2 | 98.1 | |||||
heel bone mineral density | 6 | 93.7 | |||||
hair colour measurement | 1 | 87.2 | |||||
BMI-adjusted hip circumference | 10 | 84.1 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | two pore segment channel 2 | VGNC:53181 | 747605 | |||||
Macaque | two pore segment channel 2 | 709391 | ||||||
Mouse | MGI:2385297 | 233979 | ||||||
Rat | RGD:1311779 | 309139 | ||||||
Dog | two pore segment channel 2 | VGNC:47733 | 483683 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | two pore segment channel 2 | |||||
Macaque | two pore segment channel 2 | |||||
Mouse | ||||||
Rat | ||||||
Dog | two pore segment channel 2 | |||||
PMID | Year | Title |
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