Tbio CEP70 Centrosomal protein of 70 kDa

Protein Summary

Description

Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.

Uniprot Accession IDs

• Q8NHQ1
• B7Z5I8
• B7Z7E8
• D3DNE9
• F5GZX8
• Q96B31
• Q9H2C3
• Q9H2Z1
• Q9H940
• Cep70

Gene Name

• CEP70

Ensembl ID

• ENST00000264982
• ENSP00000264982
• ENSG00000114107
• ENST00000464035
• ENSP00000419743
• ENST00000474781
• ENSP00000419833
• ENST00000481834
• ENSP00000417465
• ENST00000484888
• ENSP00000419231

Symbol

• BITE
• BITE

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.88
transcription factor binding site profile	0.86
virus perturbation	0.79
tissue sample	0.66
cellular component	0.62

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 215.05   (req: < 5)

Gene RIFs: 11   (req: <= 3)

Antibodies: 179   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 215.05   (req: >= 5)

Gene RIFs: 11   (req: > 3)

Antibodies: 179   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0