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Tdark
OR6P1
Olfactory receptor 6P1

Protein Summary
Description
Odorant receptor. Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000334632
  • ENSP00000334721
  • ENSG00000186440
  • ENST00000641540
  • ENSP00000492936
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.92
tissue
0.88
cell line
0.42
chemical
0.41
protein domain
0.41


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
View Publications
Gene RIFs: 0   (req: <= 3)
Antibodies: 46   (req: <= 50)
View Antibodies
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 46   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
View GO Terms
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Pathways (6)
G alpha (s) signalling events (R-HSA-418555)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
G alpha (s) signalling events
577 targets
R-HSA-418555
Reactome
GPCR downstream signalling
1152 targets
R-HSA-388396
Reactome
Olfactory Signaling Pathway
431 targets
R-HSA-381753
Reactome
Signal Transduction
2704 targets
R-HSA-162582
Reactome
Signaling by GPCR
1212 targets
R-HSA-372790
Name
Explore in Pharos
Explore in Source
G alpha (s) signalling events
577 targets
R-HSA-418555
GPCR downstream signalling
1152 targets
R-HSA-388396
Olfactory Signaling Pathway
431 targets
R-HSA-381753
Signal Transduction
2704 targets
R-HSA-162582
Signaling by GPCR
1212 targets
R-HSA-372790
Gene Ontology Terms (4)
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
olfactory receptor activity
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
G protein-coupled receptor activity
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Protein-Protein Interactions (27)
1 – 10 of 27
RTP1
Tbio
Novelty: 0.04761905
Score: 0.935
Data Source: STRINGDB
RTP2
Tbio
Novelty: 0.13129103
Score: 0.915
Data Source: STRINGDB
RTP3
Tbio
Novelty: 0.12230635
Score: 0.913
Data Source: STRINGDB
RTP4
Tbio
Novelty: 0.18444058
Score: 0.906
Data Source: STRINGDB
GNAL
Tbio
Novelty: 0.0277957
Score: 0.905
Data Source: STRINGDB
REEP5
Tbio
Novelty: 0.00356586
Score: 0.9
Data Source: STRINGDB
GNGT1
Tbio
Novelty: 0.03653174
Score: 0.9
Data Source: STRINGDB
GNB1
Tbio
Novelty: 0.04716243
Score: 0.9
Data Source: STRINGDB
REEP3
Tbio
Novelty: 0.28483354
Score: 0.9
Data Source: STRINGDB
REEP2
Tdark
Novelty: 0.28121006
Score: 0.9
Data Source: STRINGDB
Publication Statistics
Patents
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer
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