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Tbio
NLGN4Y
Neuroligin-4, Y-linked

Protein Summary
Description
Putative neuronal cell surface protein involved in cell-cell-interactions. This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000339174
  • ENSP00000342535
  • ENSG00000165246
  • ENST00000355905
  • ENSP00000348169
  • ENST00000382872
  • ENSP00000372325

Symbol
  • KIAA0951
  • HNL4Y
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.73
virus perturbation
0.72
microRNA
0.6
cell type or tissue
0.56
kinase perturbation
0.48


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: < 5)
Gene RIFs: 7   (req: <= 3)
Antibodies: 132   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0   (req: >= 5)
Gene RIFs: 7   (req: > 3)
Antibodies: 132   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 13
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Protein-Protein Interactions (3)
1 – 3 of 3
NLGN3
Tbio
Family:  Enzyme
Novelty:  0.00819625
p_int:  1
Data Source:  BioPlex
PRIM1
Tbio
Family:  Enzyme
Novelty:  0.0530384
p_int:  0.999636142
p_ni:  0.000363858
Data Source:  BioPlex
PRIM2
Tbio
Family:  Enzyme
Novelty:  0.05145449
p_int:  0.998068671
p_ni:  0.001931329
Data Source:  BioPlex
Pathways (4)
Neurexins and neuroligins (R-HSA-6794361)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Neurexins and neuroligins
Reactome
Neuronal System
Reactome
Protein-protein interactions at synapses
Name
Explore in Pharos
Explore in Source
Neurexins and neuroligins
Neuronal System
Protein-protein interactions at synapses
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
neuroligin 4 Y-linked
VGNC:5886
449030
Xenopus
neuroligin 4, X-linked
XB-GENE-6036018
100329189
Species
Name
OMA
EggNOG
Inparanoid
Chimp
neuroligin 4 Y-linked
Xenopus
neuroligin 4, X-linked
Publication Statistics
PubTator Score 2.64
PubTator score by year