Tbio ABHD11 Protein ABHD11

Protein Summary

Description

This gene encodes a protein containing an alpha/beta hydrolase fold domain. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. [provided by RefSeq, Mar 2016]

Uniprot Accession IDs

• Q8NFV4
• H7BYM8
• Q6PJU0
• Q8N722
• Q8N723
• Q8NFV2
• Q8NFV3
• Q9HBS8

Gene Name

• ABHD11

Ensembl ID

• ENST00000222800
• ENSP00000222800
• ENSG00000106077
• ENST00000357419
• ENSP00000392945
• ENST00000395147
• ENSP00000378579
• ENST00000437775
• ENSP00000416970

Symbol

• WBSCR21
• PP1226
• WBSCR21

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor binding site profile	0.9
histone modification site profile	0.85
kinase perturbation	0.71
transcription factor	0.63
cell type or tissue	0.61

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.39   (req: < 5)

Gene RIFs: 8   (req: <= 3)

Antibodies: 115   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.39   (req: >= 5)

Gene RIFs: 8   (req: > 3)

Antibodies: 115   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0