You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
BPIFB6
BPI fold-containing family B member 6

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000349552
  • ENSP00000344929
  • ENSG00000167104

Symbol
  • BPIL3
  • BPIL3
  • LPLUNC6
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.88
interacting protein
0.65
tissue
0.42
protein complex
0.41
protein domain
0.41


Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.66   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 62   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.66   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
non-melanoma skin carcinoma
1
1
0
1.3
56.2
alcohol consumption measurement
1
1
1
24.5
1
1
1
13.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
non-melanoma skin carcinoma
0
1.3
56.2
alcohol consumption measurement
1
24.5
1
13.3
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
BPI fold containing family B member 6
VGNC:6060
746728
Macaque
BPI fold containing family B member 6
710835
Mouse
MGI:2684965
228796
Dog
BPI fold containing family B member 6
VGNC:38511
609958
Horse
BPI fold containing family B member 6
VGNC:15872
100068780
Species
Name
OMA
EggNOG
Inparanoid
Chimp
BPI fold containing family B member 6
Macaque
BPI fold containing family B member 6
Mouse
Dog
BPI fold containing family B member 6
Horse
BPI fold containing family B member 6
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-Q8NFQ5-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Pathways (3)
Antimicrobial peptides (R-HSA-6803157)

Click on a row in the table to change the structure displayed.

Items per page:
1 – 3 of 3
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Antimicrobial peptides
Reactome
Immune System
Reactome
Innate Immune System
Name
Explore in Pharos
Explore in Source
Antimicrobial peptides
Immune System
Innate Immune System
Gene Ontology Terms (2)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (24)
1 – 10 of 24
BPIFA3
Tdark
Novelty:  2.57247859
Score:  0.802
Data Source:  STRINGDB
BPIFA1
Tbio
Novelty:  0.00586117
Score:  0.688
Data Source:  STRINGDB
BPIFB1
Tbio
Novelty:  0.03980683
Score:  0.681
Data Source:  STRINGDB
BPIFA2
Tbio
Novelty:  0.01533858
Score:  0.621
Data Source:  STRINGDB
SUN5
Tbio
Novelty:  0.04753659
Score:  0.581
Data Source:  STRINGDB
COMMD7
Tbio
Novelty:  0.10293755
Score:  0.518
Data Source:  STRINGDB
TSHB
Tbio
Novelty:  0.00194403
Score:  0.514
Data Source:  STRINGDB
LHX3
Tbio
Family:  TF
Novelty:  0.00784158
Score:  0.512
Data Source:  STRINGDB
GHRHR
Tclin
Family:  GPCR
Novelty:  0.00637611
Score:  0.512
Data Source:  STRINGDB
CGA
Tbio
Novelty:  0.00394017
Score:  0.511
Data Source:  STRINGDB
Publication Statistics
PubMed Score  1.66

PubMed score by year
PubTator Score  1.53

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer