Tbio FLAD1 FAD synthase

Protein Summary

Description

Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. This gene encodes the enzyme that catalyzes adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• Q8NFF5
• Q8N5J1
• Q8N686
• Q8WU93
• Q8WUJ4
• Q96CR8
• Q99764
• Q9HBN6

Gene Name

• FLAD1

Ensembl ID

• ENST00000292180
• ENSP00000292180
• ENSG00000160688
• ENST00000315144
• ENSP00000317296
• ENST00000368431
• ENSP00000357416
• ENST00000368432
• ENSP00000357417

Symbol

• FAD1
• FADS
• PP591
• LSMFLAD

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
molecular function	0.9
disease perturbation	0.79
transcription factor binding site profile	0.77
transcription factor	0.72
kinase perturbation	0.71

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.51   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 141   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 52.51   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 141   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0