Protein Summary
Involved in the translational repression of cytoplasmic polyadenylation element (CPE)-containing mRNAs. Neuroguidin is an EIF4E (MIM 133440)-binding protein that interacts with CPEB (MIM 607342) and functions as a translational regulatory protein during development of the vertebrate nervous system (Jung et al., 2006 [PubMed 16705177]).[supplied by OMIM, Mar 2008]
- ENST00000397154
- ENSP00000380340
- ENSG00000129460
- ENST00000408901
- ENSP00000386134
- C14orf120
- NGD
- LCP5
- CANu1
- lpd-2
- C14orf120
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.94 | ||
kinase perturbation | 0.93 | ||
transcription factor binding site profile | 0.84 | ||
transcription factor perturbation | 0.84 | ||
disease perturbation | 0.83 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 70.46 (req: < 5)
Gene RIFs: 3 (req: <= 3)
Antibodies: 130 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 70.46 (req: >= 5)
Gene RIFs: 3 (req: > 3)
Antibodies: 130 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 3
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (281)
NOL10
Novelty: 0.27358884
p_int: 0.999988763
p_ni: 0.000011234
p_wrong: 3e-9
Score: 0.997
Data Source: BioPlex,STRINGDB
RPS2
Novelty: 0.00412313
p_int: 0.961164377
p_ni: 0.038835622
p_wrong: 1e-9
Score: 0.184
Data Source: BioPlex,STRINGDB
ZNF512
Family: TF
Novelty: 0.08783629
p_int: 0.954318935
p_ni: 0.045662945
p_wrong: 0.000018121
Score: 0.209
Data Source: BioPlex,STRINGDB
HIST1H1T
Novelty: 0.01039464
p_int: 0.951029521
p_ni: 0.048969568
p_wrong: 9.11e-7
Data Source: BioPlex
RPS14
Novelty: 0.00576737
p_int: 0.929377893
p_ni: 0.070622096
p_wrong: 1.1e-8
Score: 0.485
Data Source: BioPlex,STRINGDB
RPL18A
Novelty: 0.04612948
p_int: 0.910315545
p_ni: 0.089684411
p_wrong: 4.4e-8
Score: 0.178
Data Source: BioPlex,STRINGDB
GPATCH4
Novelty: 1.13040547
p_int: 0.878924914
p_ni: 0.121075004
p_wrong: 8.2e-8
Score: 0.563
Data Source: BioPlex,STRINGDB
RPS16
Novelty: 0.00261983
p_int: 0.876697621
p_ni: 0.123302365
p_wrong: 1.5e-8
Score: 0.468
Data Source: BioPlex,STRINGDB
FGF17
Novelty: 0.01432991
p_int: 0.848167247
p_ni: 0.151832669
p_wrong: 8.5e-8
Data Source: BioPlex
RNF151
Novelty: 2.0077961
p_int: 0.815183609
p_ni: 0.184813793
p_wrong: 0.000002598
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (11)
Functions (1)
Components (8)
Processes (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Disease Associations ()
GWAS Traits (11)
Items per page:
1 – 5 of 11
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
electrocardiography | 2 | 1 | 61 | 5.3 | 83.4 | ||||
heart rate | 2 | 1 | 1 | 5.3 | 83.3 | ||||
2 | 2 | 0 | 1.1 | 74.6 | |||||
P wave terminal force measurement | 1 | 1 | 0 | 133.5 | 74.5 | ||||
resting heart rate | 1 | 2 | 0 | 7.6 | 72.4 | ||||
Items per page:
1 – 5 of 11
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
electrocardiography | 61 | 5.3 | 83.4 | ||||
heart rate | 1 | 5.3 | 83.3 | ||||
0 | 1.1 | 74.6 | |||||
P wave terminal force measurement | 0 | 133.5 | 74.5 | ||||
resting heart rate | 0 | 7.6 | 72.4 | ||||
Find similar targets by:
IDG Resources
Orthologs (14)
1 – 5 of 14
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | neuroguidin | VGNC:3377 | 452802 | |||||
Macaque | neuroguidin | 714177 | ||||||
Mouse | MGI:1916216 | 68966 | ||||||
Rat | RGD:1310211 | 305887 | ||||||
Dog | neuroguidin | VGNC:43794 | 490612 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | neuroguidin | |||||
Macaque | neuroguidin | |||||
Mouse | ||||||
Rat | ||||||
Dog | neuroguidin | |||||
Publication Statistics
PubMed Score 70.46
PubMed score by year
PubTator Score 12.89
PubTator score by year
Related Publications
Text Mined References (15)
GeneRif Annotations (3)
Items per page:
0 of 0
PMID | Year | Title |
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