PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
protein domain | 0.99 | ||
molecular function | 0.94 | ||
disease perturbation | 0.93 | ||
biological process | 0.88 | ||
kinase perturbation | 0.88 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Autophagy | ||||
Reactome | Cellular responses to external stimuli | ||||
Reactome | Cytokine Signaling in Immune system | ||||
Reactome | FLT3 Signaling | ||||
Reactome | IGF1R signaling cascade | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Autophagy | ||||
Cellular responses to external stimuli | ||||
Cytokine Signaling in Immune system | ||||
FLT3 Signaling | ||||
IGF1R signaling cascade | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Direct Assay (IDA) | MGI | |||
Inferred from Mutant Phenotype (IMP) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | Ensembl | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
body height | 1 | 1 | 1 | 49.5 | |||||
comparative body size at age 10, self-reported | 1 | 1 | 1 | 8.6 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
body height | 1 | 49.5 | |||||
comparative body size at age 10, self-reported | 1 | 8.6 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | phosphatidylinositol 3-kinase catalytic subunit type 3 | VGNC:7328 | 455385 | |||||
Macaque | phosphatidylinositol 3-kinase catalytic subunit type 3 | 693918 | ||||||
Mouse | MGI:2445019 | 225326 | ||||||
Rat | RGD:620899 | 65052 | ||||||
Dog | phosphatidylinositol 3-kinase catalytic subunit type 3 | VGNC:44554 | 490477 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | phosphatidylinositol 3-kinase catalytic subunit type 3 | |||||
Macaque | phosphatidylinositol 3-kinase catalytic subunit type 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | phosphatidylinositol 3-kinase catalytic subunit type 3 | |||||
PMID | Year | Title |
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